Acetone → Ethyl 2,6-bis(trifluoromethyl)-4-isopropoxy-5-methyl-3-pyridinecarboxylate

Reaction equation

[C:22](=[O:23])([O-:24])[O-:25].[CH3:32][C:33](=[O:34])[CH3:35].[CH:28]([CH3:29])([CH3:30])[I:31].[F:1][C:2]([c:3]1[n:4][c:5]([C:16]([F:17])([F:18])[F:19])[c:6]([CH3:15])[c:7]([OH:14])[c:8]1[C:9](=[O:10])[O:11][CH2:12][CH3:13])([F:20])[F:21].[K+:26].[K+:27]>>[F:1][C:2]([c:3]1[n:4][c:5]([C:16]([F:17])([F:18])[F:19])[c:6]([CH3:15])[c:7]([O:14][CH:28]([CH3:29])[CH3:30])[c:8]1[C:9](=[O:10])[O:11][CH2:12][CH3:13])([F:20])[F:21]

Participants

Reactant 5

HCID 180Acetone

HCID 813Potassium Cation2×

HCID 6362Isopropyl iodide

HCID 19660Carbonate Ion

HCID 178469144HCID 178469144, compound

Product 1

HCID 13882899Ethyl 2,6-bis(trifluoromethyl)-4-isopropoxy-5-methyl-3-pyridinecarboxylate

Sources & evidence

ORD record: ord-725101cab9c14425ac7a6dc8783b93c3
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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