Sodium Ion → [2-(2,6-Dichloro-phenyl)-ethyl]-(3-iodo-benzyl)-amine

Reaction equation

[C:21]([O:22][BH-:23]([O:24][C:25](=[O:26])[CH3:27])[O:28][C:29](=[O:30])[CH3:31])(=[O:32])[CH3:33].[Cl:1][c:2]1[c:3]([CH2:9][CH2:10][NH2:11])[c:4]([Cl:8])[cH:5][cH:6][cH:7]1.[Cl:37][CH2:38][Cl:39].[I:12][c:13]1[cH:14][c:15]([CH:16]=[O:17])[cH:18][cH:19][cH:20]1.[Na+:34].[Na+:36].[OH-:35]>>[Cl:1][c:2]1[c:3]([CH2:9][CH2:10][NH:11][CH2:16][c:15]2[cH:14][c:13]([I:12])[cH:20][cH:19][cH:18]2)[c:4]([Cl:8])[cH:5][cH:6][cH:7]1

Participants

Reactant 6

HCID 923Sodium Ion2×

HCID 961Hydroxide

HCID 6344Dichloromethane

HCID 2526103-Iodobenzaldehyde

HCID 2724942Triacetoxyborohydride

HCID 27341012,6-Dichlorophenethylamine

Product 1

HCID 67165340[2-(2,6-Dichloro-phenyl)-ethyl]-(3-iodo-benzyl)-amine

Sources & evidence

ORD record: ord-36b297e4c9ac4ff0b116fa3217b3b61f
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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