6-Chloronicotinoyl Chloride → 6-chloro-N-[5-(3-fluoro-5-morpholinobenzamido)-2-methylphenyl]pyridine-3-carboxamide
Reaction equation
[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:8](=[O:9])[Cl:10])[cH:6][n:7]1.[NH2:11][c:12]1[cH:13][c:14]([NH:19][C:20]([c:21]2[cH:22][c:23]([F:33])[cH:24][c:25]([N:27]3[CH2:28][CH2:29][O:30][CH2:31][CH2:32]3)[cH:26]2)=[O:34])[cH:15][cH:16][c:17]1[CH3:18]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:8](=[O:9])[NH:11][c:12]2[cH:13][c:14]([NH:19][C:20]([c:21]3[cH:22][c:23]([F:33])[cH:24][c:25]([N:27]4[CH2:28][CH2:29][O:30][CH2:31][CH2:32]4)[cH:26]3)=[O:34])[cH:15][cH:16][c:17]2[CH3:18])[cH:6][n:7]1Participants
3
Sources & evidence
- ORD record
- ord-434cac6bb06d4e2dba053c8d55c502e9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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