4-Hydroxy-4-isothiazol-5-yl-cyclohexanone → N-{[1-(4-Hydroxy-4-isothiazol-5-yl-cyclohexyl)-azetidin-3-ylcarbamoyl]-methyl}-3-trifluoromethyl-benzamide
Reaction equation
[NH:14]1[CH2:15][CH:16]([NH:18][C:19](=[O:20])[CH2:21][NH:22][C:23]([c:24]2[cH:25][c:26]([C:30]([F:31])([F:32])[F:33])[cH:27][cH:28][cH:29]2)=[O:34])[CH2:17]1.[OH:1][C:2]1([c:9]2[cH:10][cH:11][n:12][s:13]2)[CH2:3][CH2:4][C:5](=[O:8])[CH2:6][CH2:7]1>>[OH:1][C:2]1([c:9]2[cH:10][cH:11][n:12][s:13]2)[CH2:3][CH2:4][CH:5]([N:14]2[CH2:15][CH:16]([NH:18][C:19](=[O:20])[CH2:21][NH:22][C:23]([c:24]3[cH:25][c:26]([C:30]([F:31])([F:32])[F:33])[cH:27][cH:28][cH:29]3)=[O:34])[CH2:17]2)[CH2:6][CH2:7]1Participants
3
Sources & evidence
- ORD record
- ord-9c94e0fdc31c47beb99ed18e523012b7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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