3-(2-Methoxyethyl)-2,3,4,5-tetrahydro-1h-3-benzazepin-7-amine → 5-Bromo-2-{5-chloro-2-[3-(2-methoxy-ethyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ylamino]-pyrimidin-4-ylamino}-3-fluoro-N-methyl-benzamide
Reaction equation
[Br:17][c:18]1[cH:19][c:20]([F:37])[c:21]([NH:28][c:29]2[n:30][c:31]([Cl:36])[n:32][cH:33][c:34]2[Cl:35])[c:22]([C:23](=[O:24])[NH:25][CH3:26])[cH:27]1.[CH3:1][O:2][CH2:3][CH2:4][N:5]1[CH2:6][CH2:7][c:8]2[c:9]([cH:12][c:13]([NH2:16])[cH:14][cH:15]2)[CH2:10][CH2:11]1>>[CH3:1][O:2][CH2:3][CH2:4][N:5]1[CH2:6][CH2:7][c:8]2[c:9]([cH:12][c:13]([NH:16][c:31]3[n:30][c:29]([NH:28][c:21]4[c:20]([F:37])[cH:19][c:18]([Br:17])[cH:27][c:22]4[C:23](=[O:24])[NH:25][CH3:26])[c:34]([Cl:35])[cH:33][n:32]3)[cH:14][cH:15]2)[CH2:10][CH2:11]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-be69d114fd044f7987ef8ad305320fba
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)