HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphate → 2-Amino-6-tert-butyl-benzothiazole-4-thiol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphate | HCID 1061 | — |
| Reactant | D-1,4-Dithiothreitol | HCID 446094 | — |
| Reactant | 6-Tert-butyl-4-thiocyanato-benzothiazol-2-yl-amine | HCID 15473842 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Amino-6-tert-butyl-benzothiazole-4-thiol | HCID 22572780 | — |
Reaction Steps
The title compound was prepared according to General Method 14 using 6-tert-butyl-4-thiocyanato-benzothiazol-2-yl-amine (Example L-6; 2.0 g. 7.6 mmol), dithiothreitol (4.6 g, 30 mmol), phosphate buffer of pH 7 (10 mL), and EtOH (50 mL). The crude product was used further without any purification. MS (APCI): 239 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06852711B2 |
| Source dataset | uspto-grants-2005_02 |
| ORD ID | ord-c023bb652b76466495c6fd9c9529320f |
| Source note | uspto-grants-2005_02 |