Dichloromethane → tert-butyl N-(4-(chloromethyl)pyridin-2-yl)carbamate

HRID 2348866

Reaction equation

HRID 2348866 reaction equation
[Cl:21][CH2:22][Cl:23].[OH:1][CH2:2][c:3]1[cH:4][c:5]([NH:9][C:10]([O:11][C:12]([CH3:13])([CH3:14])[CH3:15])=[O:16])[n:6][cH:7][cH:8]1.[S:17]([Cl:18])([Cl:19])=[O:20]>>[CH2:2]([c:3]1[cH:4][c:5]([NH:9][C:10]([O:11][C:12]([CH3:13])([CH3:14])[CH3:15])=[O:16])[n:6][cH:7][cH:8]1)[Cl:19]

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 24386Thionyl ChlorideHCID 231510012-(Boc-amino)-4-(hydroxymethyl)pyridine

Product 1

HCID 21068467tert-butyl N-(4-(chloromethyl)pyridin-2-yl)carbamate

Sources & evidence

ORD record
ord-04a32dadbb3342b8bd25d39fe83af3c0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Linked notes

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