{1-[4-(6-Fluoro-4-oxo-2-phenyl-4H-chromen-3-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester → (1-{4-[7-(2-Hydroxy-ethyl)-4,8-dioxo-2-phenyl-7,8-dihydro-4H-pyrano[2,3-c]pyridin-3-yl]-phenyl}-cyclobutyl)-carbamic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][C:8]1([c:12]2[cH:13][cH:14][c:15](-[c:18]3[c:19](=[O:20])[c:21]4[c:22]([cH:23][cH:24][c:25]([F:26])[cH:27]4)[o:28][c:29]3-[c:30]3[cH:31][cH:32][cH:33][cH:34][cH:35]3)[cH:16][cH:17]2)[CH2:9][CH2:10][CH2:11]1)=[O:36].[OH:37][CH2:38][CH2:39][n:40]1[c:41](=[O:58])[c:42]2[c:43]([cH:44][cH:45]1)[c:46](=[O:57])[c:47]([I:56])[c:48](-[c:50]1[cH:51][cH:52][cH:53][cH:54][cH:55]1)[o:49]2>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][C:8]1([c:12]2[cH:13][cH:14][c:15](-[c:47]3[c:46](=[O:57])[c:43]4[c:42]([c:41](=[O:58])[n:40]([CH2:39][CH2:38][OH:37])[cH:45][cH:44]4)[o:49][c:48]3-[c:50]3[cH:51][cH:52][cH:53][cH:54][cH:55]3)[cH:16][cH:17]2)[CH2:9][CH2:10][CH2:11]1)=[O:36]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-69cdc6624ca84fe79a269d2e7a80e7b6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)