O-Phenylenediamine → HCID 178419295, compound

HRID 235256

Reaction equation

HRID 235256 reaction equation
[Br:1][C:2]1[CH:10]=[C:9]2[C:5]([C:6](=O)[C:7](=O)[NH:8]2)=[CH:4][CH:3]=1.[C:13]1([NH2:20])[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[NH2:19]>C(O)(=O)CCC>[Br:1][C:2]1[CH:3]=[CH:4][C:5]2[C:6]3[C:7]([NH:19][C:14]4[C:13]([N:20]=3)=[CH:18][CH:17]=[CH:16][CH:15]=4)=[N:8][C:9]=2[CH:10]=1

Participants

4

Reactant 2

HCID 7243O-PhenylenediamineHCID 957161H-Indole-2,3-dione, 6-bromo-

Product 1

HCID 178419295HCID 178419295, compound

Reagents, catalysts & solvents 1

HCID 264Butyric AcidSolvent

Procedure

A solution of 15.18 g (67.2 mmol) of 6-bromoisatin and 7.26 g (1.0 eq.) of 1,2-phenylenediamine in 250 ml of butyric acid was refluxed for 4 hours, followed by allowing to stand at room temperature for 16 hours. The precipitate was collected by filtration to give 8-bromoindolo[2,3-b]quinoxaline.

Workup

  1. filtrationThe precipitate was collected by filtration

Sources & evidence

ORD record
ord-8cf9452ba60643d19233af36ff4282ad
Source dataset
uspto-grants-1997_01
Patent number
US05597921

Linked notes

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