2-Amino-4-chlorobenzaldehyde → HCID 68553898, compound

Reaction equation

[NH2:1][C:2]1[CH:9]=[C:8]([Cl:10])[CH:7]=[CH:6][C:3]=1[CH:4]=O.[Cl:11][C:12]1[CH:17]=[CH:16][CH:15]=[C:14]([O:18][CH3:19])[C:13]=1[CH2:20][CH2:21][C:22]#[N:23]>>[Cl:10][C:8]1[CH:9]=[C:2]2[C:3]([CH:4]=[C:21]([CH2:20][C:13]3[C:14]([O:18][CH3:19])=[CH:15][CH:16]=[CH:17][C:12]=3[Cl:11])[C:22]([NH2:23])=[N:1]2)=[CH:6][CH:7]=1

Participants

Reactant 2

HCID 112521382-Amino-4-chlorobenzaldehyde

HCID 685518043-(2-Chloro-6-methoxyphenyl)propanenitrile

Product 1

HCID 68553898HCID 68553898, compound

Procedure

The title compound was synthesized according to EXAMPLE 11 from 2-amino-4-chlorobenzaldehyde and 3-(2-chloro-6-methoxyphenyl)propionitrile.

Sources & evidence

ORD record: ord-4d06f2e9eedc47ad8b2c51ea046f03c9
Source dataset: uspto-grants-2014_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08686002B2

Reaction notes

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