3-(2-Methoxyphenyl)propanenitrile → HCID 68553337, compound

Reaction equation

[NH2:1][C:2]1[CH:9]=[CH:8][C:7]([O:10][CH2:11][CH3:12])=[CH:6][C:3]=1[CH:4]=O.[CH3:13][O:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=1[CH2:21][CH2:22][C:23]#[N:24]>>[CH2:11]([O:10][C:7]1[CH:6]=[C:3]2[C:2](=[CH:9][CH:8]=1)[N:1]=[C:23]([NH2:24])[C:22]([CH2:21][C:16]1[CH:17]=[CH:18][CH:19]=[CH:20][C:15]=1[O:14][CH3:13])=[CH:4]2)[CH3:12]

Participants

Reactant 2

HCID 183495903-(2-Methoxyphenyl)propanenitrile

HCID 859748662-Amino-5-ethoxybenzaldehyde

Product 1

HCID 68553337HCID 68553337, compound

Procedure

The title compound was synthesized according to EXAMPLE 11 from 2-amino-5-ethoxybenzaldehyde and 3-(2-methoxyphenyl)propionitrile.

Sources & evidence

ORD record: ord-c8d1463b0c9a408a9dc1109a27100e06
Source dataset: uspto-grants-2014_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08686002B2

Reaction notes

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