3-Aminoisonicotinaldehyde → HCID 16045946, compound

Reaction equation

[NH2:1][C:2]1[CH:3]=[N:4][CH:5]=[CH:6][C:7]=1[CH:8]=O.[CH3:10][O:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[CH2:18][CH2:19][C:20]#[N:21]>>[CH3:10][O:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[CH2:18][C:19]1[C:20]([NH2:21])=[N:1][C:2]2[C:7]([CH:8]=1)=[CH:6][CH:5]=[N:4][CH:3]=2

Participants

Reactant 2

HCID 27630013-Aminoisonicotinaldehyde

HCID 183495903-(2-Methoxyphenyl)propanenitrile

Product 1

HCID 16045946HCID 16045946, compound

Procedure

The title compound was synthesized according to EXAMPLE 11 from 3-amino-4-pyridine carboxaldehyde and 3-(2-methoxyphenyl)propionitrile.

Sources & evidence

ORD record: ord-1f71be75ebc74c42a3e67ab9d14432c2
Source dataset: uspto-grants-2014_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08686002B2

Reaction notes

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