3-Aminoisonicotinaldehyde → HCID 68554071, compound

Reaction equation

[NH2:1][C:2]1[CH:3]=[N:4][CH:5]=[CH:6][C:7]=1[CH:8]=O.[CH3:10][O:11][C:12]1[CH:17]=[CH:16][CH:15]=[C:14]([O:18][CH3:19])[C:13]=1[CH2:20][CH2:21][C:22]#[N:23]>>[CH3:19][O:18][C:14]1[CH:15]=[CH:16][CH:17]=[C:12]([O:11][CH3:10])[C:13]=1[CH2:20][C:21]1[C:22]([NH2:23])=[N:1][C:2]2[C:7]([CH:8]=1)=[CH:6][CH:5]=[N:4][CH:3]=2

Participants

Reactant 2

HCID 27630013-Aminoisonicotinaldehyde

HCID 21850027HCID 21850027, compound

Product 1

HCID 68554071HCID 68554071, compound

Procedure

The title compound was synthesized according to EXAMPLE 11 from 3-amino-4-pyridine carboxaldehyde and 3-(2,6-dimethoxyphenyl)propionitrile

Sources & evidence

ORD record: ord-1a3156fa816e4a78822960de732069e4
Source dataset: uspto-grants-2014_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08686002B2

Reaction notes

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