4-Aminonicotinaldehyde → HCID 68550117, compound

Reaction equation

[NH2:1][C:2]1[C:7]([CH:8]=O)=[CH:6][N:5]=[CH:4][CH:3]=1.[Cl:10][C:11]1[CH:16]=[CH:15][CH:14]=[C:13]([O:17][CH3:18])[C:12]=1[CH2:19][CH2:20][C:21]#[N:22]>>[Cl:10][C:11]1[CH:16]=[CH:15][CH:14]=[C:13]([O:17][CH3:18])[C:12]=1[CH2:19][C:20]1[C:21]([NH2:22])=[N:1][C:2]2[C:7]([CH:8]=1)=[CH:6][N:5]=[CH:4][CH:3]=2

Participants

Reactant 2

HCID 27610334-Aminonicotinaldehyde

HCID 685518043-(2-Chloro-6-methoxyphenyl)propanenitrile

Product 1

HCID 68550117HCID 68550117, compound

Procedure

The title compound was synthesized according to EXAMPLE 11 from 4-aminonicotinaldehyde and 3-(2-chloro-6-methoxyphenyl)propionitrile.

Sources & evidence

ORD record: ord-24f9f4b7f3ae461ca98bf1aece65b5f9
Source dataset: uspto-grants-2014_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08686002B2

Reaction notes

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