HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromopyridine → 8-(2-Pyridinyl)-1,4-dioxa-8-azaspiro[4.5]decane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromopyridine | HCID 7973 | — |
| Reactant | 1,4-Dioxa-8-azaspiro(4.5)decane | HCID 67435 | — |
| Reagent | Sodium t-butoxide | HCID 23676156 | — |
| Catalyst | Palladium (II) acetate | HCID 4144353 | — |
| Catalyst | 2-Dicyclohexylphosphino-2',4',6'-triisoprophylbiphenyl | HCID 11155794 | — |
| Product | 8-(2-Pyridinyl)-1,4-dioxa-8-azaspiro[4.5]decane | HCID 12033765 | 66.56% |
Reaction Steps
The same procrdure as EN03653-93-01.
Provenance & Evidence
| Source dataset | 750 AstraZeneca ELN dataset |
|---|---|
| ORD ID | ord-00b95f6f20354bb6923efd18c2b3c116 |
| Source note | 750 AstraZeneca ELN dataset |