(3aR,4S,6aS)-2-(6-(trifluoromethyl)pyridin-2-yl)octahydrocyclopenta[c]pyrrol-4-amine → (2S,3aS,7aS)-N-{(3aR,4S,6aS)-2-[5-(trifluoromethyl)pyridin-2-yl]octahydrocyclopenta[c]pyrrol-4-yl}octahydro-1H-indole-2-carboxamide

Reaction equation

C(OC([N:8]([CH3:18])[C@@H:9]([CH2:13][C:14]([CH3:17])(C)C)[C:10]([OH:12])=O)=O)(C)(C)C.[F:19][C:20]([F:37])([F:36])[C:21]1[CH:22]=[CH:23][C:24]([N:27]2[CH2:31][C@@H:30]3[C@@H:32]([NH2:35])[CH2:33][CH2:34][C@@H:29]3[CH2:28]2)=[N:25][CH:26]=1.F[C:39](F)(F)[C:40]1N=C(N2C[C@@H]3[C@@H](N)CC[C@@H]3C2)C=C[CH:41]=1>>[F:37][C:20]([F:19])([F:36])[C:21]1[CH:22]=[CH:23][C:24]([N:27]2[CH2:31][C@@H:30]3[C@@H:32]([NH:35][C:10]([C@@H:9]4[CH2:13][C@H:14]5[C@H:18]([CH2:39][CH2:40][CH2:41][CH2:17]5)[NH:8]4)=[O:12])[CH2:33][CH2:34][C@@H:29]3[CH2:28]2)=[N:25][CH:26]=1