Furoin → HCID 178527844, compound

HRID 237005

Reaction equation

HRID 237005 reaction equation
[CH:1]1[CH:5]=[C:4]([CH:6](O)[C:7]([C:9]2[O:13][CH:12]=[CH:11][CH:10]=2)=O)[O:3][CH:2]=1.[S-:15][C:16]#[N:17].[NH4+:18]>C(O)C>[O:3]1[CH:2]=[CH:1][CH:5]=[C:4]1[C:6]1[N:17]=[C:16]([SH:15])[NH:18][C:7]=1[C:9]1[O:13][CH:12]=[CH:11][CH:10]=1

Participants

4

Reactant 2

HCID 11100FuroinHCID 15666Ammonium thiocyanate

Product 1

HCID 178527844HCID 178527844, compoundYield 49.1%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

α-Furoin (19.2 g; 0.1 mole) was reacted with 11.5 g (0.15 mole) ammonium thiocyanate in ethanol heated at reflux to afford 11.4 g of 4,5-bis-(2-furyl)-1H-2-imidazolethiol. An analytical sample was prepared by chromatography on alumina with ethanol and recrystallization from nitromethane, m.p. 279°-380° (dec.).

Workup

  1. temperatureheated
  2. temperatureat reflux

Sources & evidence

ORD record
ord-65eab635b120478aa7c2e0cef350716f
Source dataset
uspto-grants-1979_06
Patent number
US04159338

Linked notes

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