2-Acetylfuran → (1S)-2-chloro-1-(2-furyl)ethanol

HRID 23706

Reaction equation

HRID 23706 reaction equation

[Cl:1][CH2:2][C@H:3]([C:5]1[CH:10]=[CH:9][CH:8]=CN=1)[OH:4].C(C1OC=CC=1)(=[O:13])C>>[Cl:1][CH2:2][C@H:3]([C:5]1[O:13][CH:8]=[CH:9][CH:10]=1)[OH:4]

Participants

3

Reactant 2

HCID 145052-Acetylfuran

HCID 60127910(1S)-2-chloro-1-pyridin-2-ylethanol

Product 1

HCID 11378571(1S)-2-chloro-1-(2-furyl)ethanol

Procedure

As described for the preparation of (1S)-2-chloro-1-pyridin-2-ylethanol, 2-acetylfuran is converted to the title compound, isolated as an oil.

Sources & evidence

ORD record: ord-b621be05bfa64d3c9ab237ea975d4c0a
Source dataset: uspto-grants-2005_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06852731B2

Linked notes

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