Sodium Hydroxide → 2-Chloro-5-{[4-(5-chloro-isoquinolin-6-yloxy)-cyclohexylamino]-methyl}-benzenesulfonamide
Reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][NH:9][C@H:10]2[CH2:15][CH2:14][C@@H:13]([O:16][C:17]3[C:18]([Cl:27])=[C:19]4[C:24](=[CH:25][CH:26]=3)[CH:23]=[N:22][CH:21]=[CH:20]4)[CH2:12][CH2:11]2)=[CH:4][C:3]=1[S:28]([N:31]=CN(C)C)(=[O:30])=[O:29].[OH-].[Na+]>C(O)C>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][NH:9][CH:10]2[CH2:15][CH2:14][CH:13]([O:16][C:17]3[C:18]([Cl:27])=[C:19]4[C:24](=[CH:25][CH:26]=3)[CH:23]=[N:22][CH:21]=[CH:20]4)[CH2:12][CH2:11]2)=[CH:4][C:3]=1[S:28]([NH2:31])(=[O:30])=[O:29]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 65 °C