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Sodium Chloride → HCID 178446842, compound

HRID 2372836
Notes
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Reaction equation

HRID 2372836 reaction equation
Cl.[C:2](=[NH:9])(OC)[CH2:3][CH2:4][CH2:5][CH3:6].[NH2:10][CH2:11][C:12]1[CH:17]=[CH:16][C:15]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=2[C:24]#[N:25])=[CH:14][CH:13]=1.C[O-].[Na+].[Cl-].[Na+]>CO>[C:24]([C:19]1[CH:20]=[CH:21][CH:22]=[CH:23][C:18]=1[C:15]1[CH:14]=[CH:13][C:12]([CH2:11][NH:10][C:2](=[NH:9])[CH2:3][CH2:4][CH2:5][CH3:6])=[CH:17][CH:16]=1)#[N:25]
ParticipantsProcedureSources & evidenceReaction notes

Participants

6

Reactant 4

HCID 5234Sodium ChlorideHCID 13933412-[4-(Aminomethyl)phenyl]benzonitrileHCID 5743465Methyl valerimidate hydrochlorideHCID 10942334Sodium Methoxide

Product 1

HCID 178446842HCID 178446842, compound

Reagents, catalysts & solvents 1

HCID 887
Methanol
Solvent

Procedure

The title compound is prepared by stirring one equivalent of methyl valerimidate hydrochloride, one equivalent of 4-aminomethyl-2'-cyanobiphenyl, and one equivalent of sodium methoxide in methanol. The reaction mixture may then be stripped of solvent and the amidine and residual sodium chloride is used directly in the next reaction.

Sources & evidence

ORD record
ord-5a45ac59856143d1af6da106ced1c6e8
Source dataset
uspto-grants-1992_03
DOI
10.6084/m9.figshare.5104873.v1
Patent number
US05100897

Reaction notes

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On this pageParticipantsProcedureSources & evidenceReaction notes