Benzoyl chloride → HCID 58711952, compound
Reaction equation
COC1C=CC(NC2N=NC(C(NC(C3OC=CC=3)=O)C)=CN=2)=CC=1.Cl.[CH3:27][S:28][C:29]1[N:30]=[N:31][C:32]([CH:35]([NH2:37])[CH3:36])=[CH:33][N:34]=1.[C:38](Cl)(=[O:45])[C:39]1[CH:44]=[CH:43][CH:42]=[CH:41][CH:40]=1>>[CH3:27][S:28][C:29]1[N:30]=[N:31][C:32]([CH:35]([NH:37][C:38](=[O:45])[C:39]2[CH:44]=[CH:43][CH:42]=[CH:41][CH:40]=2)[CH3:36])=[CH:33][N:34]=1Participants
4
Procedure
In a similar manner as described for Intermediate 59, using 1-[3-(Methylthio)-1,2,4-triazin-6-yl]ethanamine (Intermediate 4) (1.00 g, 5.90 mmol), benzoyl chloride (0.75 mL, 6.50 mmol), to give N-{1-[3-(methylthio)-1,2,4-triazin-6-yl]ethyl}benzamide (1.35 g) as a yellow solid. MS m/z 275 (M+1).