6-Chloro-2-methyl-2,3-dihydropyridazin-3-one → 6-(4-Amino-3,5-dimethylphenyl)-2-methylpyridazin-3(2H)-one

Participants

Reaction Conditions

Reaction Steps

The title compound is prepared from 6-chloro-2-methylpyridazin-3(2H)-one and 2,6-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline following a procedure analogous to that described in Step 2 of Intermediate 62. The mixture is stirred for 12 hours at 60° C. LC (method 9): tR=0.78 min; Mass spectrum (ESI+): m/z=230 [M+H]+.

Provenance & Evidence