(1H-pyrrolo[3,2-b]pyridin-2-yl)methanol → HCID 18958302, compound

Reaction equation

O[CH2:2][C:3]1[NH:4][C:5]2[C:10]([CH:11]=1)=[N:9][CH:8]=[CH:7][CH:6]=2.Cl.[CH3:13][N:14](CC1NC2C(N=1)=NC=CC=2)[CH3:15]>>[CH3:13][N:14]([CH2:2][C:3]1[NH:4][C:5]2[C:10]([CH:11]=1)=[N:9][CH:8]=[CH:7][CH:6]=2)[CH3:15]

Participants

Reactant 2

HCID 18958292(1H-pyrrolo[3,2-b]pyridin-2-yl)methanol

HCID 18958298HCID 18958298, compound

Product 1

HCID 18958302HCID 18958302, compound

Procedure

2-Dimethylaminomethyl-4-azaindole is synthesized from 2-hydroxymethyl-4-azaindole by a procedure analogous to that described for the synthesis of 2-dimethylaminomethyl-1H-imidazo[4,5-b]pyridine monohydrochloride in the J. Het. Chem., 6, 759-760 (1969).

Sources & evidence

ORD record: ord-1a97157990074fb58245591b8ad81ab9
Source dataset: uspto-grants-1994_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05360907

Reaction notes

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