HCID 19931779, compound → HCID 53741367, compound
Reaction equation
[CH:1]1([C:4](=[O:16])[CH2:5][C:6]([C:8]2[CH:13]=[CH:12][C:11]([S:14][CH3:15])=[CH:10][N:9]=2)=[O:7])[CH2:3][CH2:2]1.CC(C)C(O)=O.[CH3:23][N:24]([CH3:27])[CH:25]=O>O1CCOCC1>[CH:1]1([C:4](=[O:16])[C:5](=[CH:23][N:24]([CH3:27])[CH3:25])[C:6]([C:8]2[CH:13]=[CH:12][C:11]([S:14][CH3:15])=[CH:10][N:9]=2)=[O:7])[CH2:3][CH2:2]1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
A mixture of 3-cyclopropyl- 1-[5-(methylsulphenyl )-pyrid-2-yl]propan- 1,3-dione (2.9 g), dimethylformamide dimethyl acetate and dioxane was stirred at room temperature overnight. It was evaporated to dryness and the residue was triturated with ether and filtered to give 3-cyclopropyl-2-(N,N-dimethylaminomethylene)-1-[5-(methylsulphenyl)-pyrid-2-yl]propan- 1,3-dione (3.24 g) as a brown solid which was used without further characterization.