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Sulfanilamide → 4-Isocyanatobenzene-1-sulfonamide

HRID 2382369
Notes
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Reaction equation

HRID 2382369 reaction equation
N1[CH2:5][CH2:4][C@@H:3]([NH:6][C:7](=[O:14])C2C=CN=CC=2)[CH2:2]1.NC1C=C[C:19]([S:22]([NH2:25])(=[O:24])=[O:23])=[CH:18]C=1>>[N:6]([C:3]1[CH:2]=[CH:18][C:19]([S:22]([NH2:25])(=[O:24])=[O:23])=[CH:5][CH:4]=1)=[C:7]=[O:14]
ParticipantsProcedureSources & evidenceReaction notes

Participants

3

Reactant 2

HCID 5333SulfanilamideHCID 66630437(R)-N-Pyrrolidin-3-yl-isonicotinamide

Product 1

HCID 214940234-Isocyanatobenzene-1-sulfonamide

Procedure

This compound is prepared analogously to Intermediate R by replacing 3-aminobenzenesulphonamide with 4-aminobenzenesulphonamide.

Sources & evidence

ORD record
ord-63ed84453a5d4d3fa644739f444289ba
Source dataset
uspto-grants-2012_09
DOI
10.6084/m9.figshare.5104873.v1
Patent number
US08258141B2

Reaction notes

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On this pageParticipantsProcedureSources & evidenceReaction notes