5-Bromosalicylic acid → 5-Bromo-N [3-bromo-5-(trifluoromethyl)phenyl]-2-hydroxybenzamide

HRID 2384404

Reaction equation

HRID 2384404 reaction equation
[Br:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[Br:12][C:13]1[CH:14]=[C:15]([CH:17]=[C:18]([C:20]([F:23])([F:22])[F:21])[CH:19]=1)[NH2:16]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([OH:11])=[C:6]([CH:10]=1)[C:7]([NH:16][C:15]1[CH:17]=[C:18]([C:20]([F:21])([F:22])[F:23])[CH:19]=[C:13]([Br:12])[CH:14]=1)=[O:9]

Participants

3

Reactant 2

HCID 69725-Bromosalicylic acidHCID 27358803-Bromo-5-(trifluoromethyl)aniline

Product 1

HCID 178602635-Bromo-N [3-bromo-5-(trifluoromethyl)phenyl]-2-hydroxybenzamideYield 73.3%

Procedure

Using 5-bromosalicylic acid and 3-bromo-5-(trifluoromethyl)aniline as the raw materials, the same operation as the example 16 gave the title compound.

Sources & evidence

ORD record
ord-09da93bd55dd4e09b2f0071d3bb6340f
Source dataset
uspto-grants-2012_09
Patent number
US08263657B2

Linked notes

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