5-Bromosalicylic acid → 5-Bromo-N-(4,5-dimethylthiazol-2-yl)-2-hydroxybenzamide

HRID 2384467

Reaction equation

HRID 2384467 reaction equation
[Br:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[NH2:12][C:13]1[S:14][C:15]([CH3:19])=[C:16]([CH3:18])[N:17]=1>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([OH:11])=[C:6]([CH:10]=1)[C:7]([NH:12][C:13]1[S:14][C:15]([CH3:19])=[C:16]([CH3:18])[N:17]=1)=[O:9]

Participants

3

Reactant 2

HCID 69725-Bromosalicylic acidHCID 732382-Amino-4,5-dimethyl-1,3-thiazole

Product 1

HCID 178602025-Bromo-N-(4,5-dimethylthiazol-2-yl)-2-hydroxybenzamideYield 14.4%

Procedure

Using 5-bromosalicylic acid and 2-amino-4,5-dimethylthiazole as the raw materials, the same operation as the example 16 gave the title compound.

Sources & evidence

ORD record
ord-83335f415fcc48949755a35f9803a01a
Source dataset
uspto-grants-2012_09
Patent number
US08263657B2

Linked notes

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