5-Bromosalicylic acid → 5-Bromo-N-(4,5-diphenylthiazol-2-yl)-2-hydroxybenzamide

HRID 2384475

Reaction equation

HRID 2384475 reaction equation
[Br:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[NH2:12][C:13]1[S:14][C:15]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)=[C:16]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[N:17]=1>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([OH:11])=[C:6]([CH:10]=1)[C:7]([NH:12][C:13]1[S:14][C:15]([C:24]2[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=2)=[C:16]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[N:17]=1)=[O:9]

Participants

3

Reactant 2

HCID 69725-Bromosalicylic acidHCID 732222-Amino-4,5-diphenylthiazole

Product 1

HCID 178602695-Bromo-N-(4,5-diphenylthiazol-2-yl)-2-hydroxybenzamide

Procedure

Using 5-bromosalicylic acid and 2-amino-4,5-diphenylthiazole as the raw materials, the same operation as the example 195(3) gave the title compound. (2-Amino-4,5-diphenylthiazole: refer to Nihon Kagaku Zasshi, 1962, 83, 209.)

Sources & evidence

ORD record
ord-e7aa31b0a4b6438ebb427c25633bce57
Source dataset
uspto-grants-2012_09
Patent number
US08263657B2

Linked notes

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