Hexahydro-1,4-diazepine → 2-[1,4]-Diazepan-1-yl-thiazol-4-one

HRID 2384716Notes

Reaction equation

HRID 2384716 reaction equation
CS[C:3]1[S:4][CH2:5][C:6](=[O:8])[N:7]=1.[NH:9]1[CH2:15][CH2:14][CH2:13][NH:12][CH2:11][CH2:10]1>>[N:9]1([C:3]2[S:4][CH2:5][C:6](=[O:8])[N:7]=2)[CH2:15][CH2:14][CH2:13][NH:12][CH2:11][CH2:10]1

Participants

3

Reactant 2

HCID 68163Hexahydro-1,4-diazepineHCID 14820222-(Methylsulfanyl)-4,5-dihydro-1,3-thiazol-4-one

Product 1

HCID 672396522-[1,4]-Diazepan-1-yl-thiazol-4-one

Procedure

2-[1,4]-Diazepan-1-yl-thiazol-4-one was prepared from 2-Methylsulfanyl-thiazol-4-one and [1,4]diazepane following General Procedure E

Sources & evidence

ORD record
ord-e5d49bf310764577b54edd9e1921e341
Source dataset
uspto-grants-2012_09
Patent number
US08263781B2

Reaction notes

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