Acetic Acid → Lactic Acid

Reaction equation

[OH:1][CH2:2][C:3]([C@H:5]([C@@H:7]([C@@H:9]([CH2:11][OH:12])[OH:10])[OH:8])[OH:6])=[O:4].C(O)(=[O:15])C>>[CH2:11]([OH:12])[C@H:9]([C@H:7]([C@@H:5]([C@@H:3]([CH2:2][OH:1])[OH:4])[OH:6])[OH:8])[OH:10].[C:11]([OH:12])(=[O:15])[CH:9]([CH3:7])[OH:10]

Participants

Reactant 2

HCID 176Acetic Acid

HCID 5984D-(-)-Fructose

Product 2

HCID 612Lactic Acid

HCID 6251Mannitol

Procedure

intermedius NRRL B-30560 was grown essentially as described in Example 2 in simplified MRS medium under anaerobic conditions using 2% fructose as the carbon source. The product patterns were analyzed by HPLC. The bacterium produced mannitol, lactic acid and acetic acid in product ratios similar to those obtained under aerobic conditions.

Sources & evidence

ORD record: ord-6bf75470768c48bdb58ede6efda21261
Source dataset: uspto-grants-2005_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06855526B2

Reaction notes

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