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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2386639Generated: October 25, 2026

8-chloro-3-(2-cyclopropylethyl)-7-(2-propen-1-yl)-3,7-dihydro-1H-purine-2,6-dione → [8-chloro-3-(2-cyclopropylethyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-1-yl]acetonitrile

https://huagongshe.com/reaction/2386639

Reaction equation

Participants

RoleNameHCIDCharge
Reactant8-chloro-3-(2-cyclopropylethyl)-7-(2-propen-1-yl)-3,7-dihydro-1H-purine-2,6-dioneHCID 59299541—
Reactant(8-chloro-2,6-dioxo-3-propyl-2,3,6,7-tetrahydro-1H-purin-1-yl)acetonitrileHCID 59299547—
Product[8-chloro-3-(2-cyclopropylethyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-1-yl]acetonitrileHCID 11737943—

Reaction Steps

Prepared as (8-chloro-2,6-dioxo-3-propyl-2,3,6,7-tetrahydro-1H-purin-1-yl)acetonitrile (example 23) using 8-chloro-3-(2-cyclopropylethyl)-7-(2-propen-1-yl)-3,7-dihydro-1H-purine-2,6-dione.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08268839B2
Source datasetuspto-grants-2012_09
ORD IDord-93fe5992a45f4a2088c8a901c859cf50
Source noteuspto-grants-2012_09