3-Methoxypropylamine → 1-Cyclohexyl-6-[(5-((3-methoxy-propyl)aminocarbonyl)pentyl)oxy]-2-phenyl-benzimidazole

HRID 23892

Reaction equation

HRID 23892 reaction equation
[CH:1]1([N:7]2[C:11]3[CH:12]=[C:13]([O:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][C:22](OC)=[O:23])[CH:14]=[CH:15][C:10]=3[N:9]=[C:8]2[C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:32][O:33][CH2:34][CH2:35][CH2:36][NH2:37]>>[CH:1]1([N:7]2[C:11]3[CH:12]=[C:13]([O:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][C:22]([NH:37][CH2:36][CH2:35][CH2:34][O:33][CH3:32])=[O:23])[CH:14]=[CH:15][C:10]=3[N:9]=[C:8]2[C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

3

Reactant 2

HCID 16723-MethoxypropylamineHCID 101591401-Cyclohexyl-6-[(5-(methoxycarbonyl)pentyl)oxy]-2-phenyl-benzimidazole

Product 1

HCID 101626831-Cyclohexyl-6-[(5-((3-methoxy-propyl)aminocarbonyl)pentyl)oxy]-2-phenyl-benzimidazole

Procedure

1-Cyclohexyl-6-[(5-(methoxycarbonyl)pentyl)oxy]-2-phenyl-benzimidazole is reacted according to general operating instructions 7 with 3-methoxypropylamine. 1-Cyclohexyl-6-[(5-((3-methoxy-propyl)aminocarbonyl)pentyl)oxy]-2-phenyl-benzimidazole is obtained as a solid.

Sources & evidence

ORD record
ord-795b65ebd8c94c5286310352245653f4
Source dataset
uspto-grants-2005_02
Patent number
US06855714B2

Linked notes

Loading…