N-methoxy-N,3-dimethylbutanamide → 4-Methyl-1-(3-toluyl)-pentan-2-one
Reaction equation
CON(C)[C:4](=[O:9])[CH2:5][CH:6]([CH3:8])[CH3:7].[CH3:11][C:12]1[CH:13]=[C:14]([CH:18]=[CH:19][CH:20]=1)[CH2:15][Mg]Cl>>[CH3:7][CH:6]([CH3:8])[CH2:5][C:4](=[O:9])[CH2:11][C:12]1[CH:13]=[C:14]([CH3:15])[CH:18]=[CH:19][CH:20]=1Participants
3
Procedure
The reaction and treatment were carried out in the same manner as in Example 36-b) using N-methoxy-N-methyl-3-methylbutanamide and 3-methylbenzyl magnesium chloride to obtain a title compound as a light yellow oily substance.
Workup
- customThe reaction and treatment
Sources & evidence
- ORD record
- ord-41b937c61668408b8e609de182fa49cf
- Source dataset
- uspto-grants-2012_09
- Patent number
- US08273766B2
Reaction notes
Loading…