HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Trifluoromethyl)phenol → 2-Hydroxy-5-trifluoromethylbenzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Trifluoromethyl)phenol | HCID 67874 | — |
| Reactant | Ethyl acetate hexane | HCID 21226206 | — |
| Product | 2-Hydroxy-5-trifluoromethylbenzaldehyde | HCID 15500988 | 34% |
Reaction Steps
Following the general procedure and FCC purification with 30% ethyl acetate-hexane, 4-trifluoromethyl phenol (10.0 g, 61.7 mmol) gave 2-hydroxy-5-trifluoromethyl-benzaldehyde 27 (3.9 g, 34%) as a pink solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06855695B2 |
| Source dataset | uspto-grants-2005_02 |
| ORD ID | ord-28e0930bac704493b0adc4c206e0474c |
| Source note | uspto-grants-2005_02 |