2-Methoxy-5-nitrophenol → 3-(2-Diisopropylaminoethoxy)-4-methoxyaniline

Reaction equation

[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([N+:9]([O-])=O)=[CH:5][C:4]=1[OH:12].Cl.[CH:14]([N:17]([CH:21]([CH3:23])[CH3:22])[CH2:18][CH2:19]Cl)([CH3:16])[CH3:15]>>[CH:14]([N:17]([CH:21]([CH3:23])[CH3:22])[CH2:18][CH2:19][O:12][C:4]1[CH:5]=[C:6]([CH:7]=[CH:8][C:3]=1[O:2][CH3:1])[NH2:9])([CH3:16])[CH3:15]

Participants

Reactant 2

HCID 694712-Methoxy-5-nitrophenol

HCID 779422-Chloroethyldiisopropylammonium chloride

Product 1

HCID 113576133-(2-Diisopropylaminoethoxy)-4-methoxyaniline

Procedure

The title compound was prepared from 2-methoxy-5-nitrophenol and 2-diisopropylaminoethyl chloride hydrochloride, following a procedure similar to that described in Descriptions 1 and 2 (81%).

Sources & evidence

ORD record: ord-cda4f54384c44a709688d3f651b027c8
Source dataset: uspto-grants-1998_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05801170

Reaction notes

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