Cyclohexyl propionate → 2-Ethoxyphenol
Reaction equation
[CH2:1]([O:3][CH:4]1[CH2:9][CH2:8][CH2:7][CH2:6][C:5]1=[O:10])[CH3:2].C1(OC(=O)CC)CCCCC1.[H][H]>[Pd]>[CH2:1]([O:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[OH:10])[CH3:2]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
A solution of 10 gm. 2-ethoxycyclohexanone in 100 ml. cyclohexylpropionate was refluxed over 400 mg. of palladium on carbon until approximately 75% hydrogen had evolved. The catalyst was removed by filtration. o-Ethoxyphenol was obtained in high yield.
Workup
- customThe catalyst was removed by filtration
Sources & evidence
- ORD record
- ord-0fd51af1e8b645e9b496c662715b6769
- Source dataset
- uspto-grants-1977_05
- Patent number
- USRE029201
Reaction notes
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