Ethyl 5-ethyl-2-methylfuran-3-carboxylate → 5-Ethyl-2-methylfuran-3-carboxylic acid
Reaction equation
[CH2:1]([C:3]1[O:7][C:6]([CH3:8])=[C:5]([C:9]([O:11]CC)=[O:10])[CH:4]=1)[CH3:2]>[OH-].[Na+]>[CH2:1]([C:3]1[O:7][C:6]([CH3:8])=[C:5]([C:9]([OH:11])=[O:10])[CH:4]=1)[CH3:2]Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
Saponification of 0.5 g of the ester was carried out by refluxing 4 hours in 10 ml of 25% aqueous sodium hydroxide. Acidification precipitated the crude acid, which was recrystallized from water to obtain 5-ethyl-2-methyl-3-furoic acid as white needles, mp 97°-99° C.
Workup
- customAcidification precipitated the crude acid, which
- customwas recrystallized from water
Sources & evidence
- ORD record
- ord-15ef1252020b4145924a8f2c09c718a7
- Source dataset
- uspto-grants-1977_05
- Patent number
- US04025537
Reaction notes
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