Isopropyl iodide → 2-(Butyloxy)-9-{5-[1-(1-methylethyl)-3-piperidinyl]pentyl}-8-(methyloxy)-9H-purin-6-amine
Reaction equation
C(N1CC[CH2:6][CH:5](CCN2C(OC)=NC3C2=NC(O[C@@H](C)CCC)=NC=3N)[CH2:4]1)C.[CH2:29]([O:33][C:34]1[N:42]=[C:41]2[C:37]([N:38]=[C:39]([O:54][CH3:55])[N:40]2[CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][CH:48]2[CH2:53][CH2:52][CH2:51][NH:50][CH2:49]2)=[C:36]([NH2:56])[N:35]=1)[CH2:30][CH2:31][CH3:32].IC(C)C>>[CH2:29]([O:33][C:34]1[N:42]=[C:41]2[C:37]([N:38]=[C:39]([O:54][CH3:55])[N:40]2[CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][CH:48]2[CH2:53][CH2:52][CH2:51][N:50]([CH:5]([CH3:6])[CH3:4])[CH2:49]2)=[C:36]([NH2:56])[N:35]=1)[CH2:30][CH2:31][CH3:32]Participants
4
Reactant 3
Product 1
Procedure
Prepared similarly to Intermediate 46 from 2-(butyloxy)-8-(methyloxy)-9-[5-(3-piperidinyl)pentyl]-9H-purin-6-amine and 2-iodopropane.