1,4-Benzenediol, 2-nitro- → Aminohydroquinone
Reaction equation
[N+:1]([C:4]1[CH:9]=[C:8]([OH:10])[CH:7]=[CH:6][C:5]=1[OH:11])([O-])=O.[H][H]>C(O)C.[Pd]>[NH2:1][C:4]1[CH:9]=[C:8]([OH:10])[CH:7]=[CH:6][C:5]=1[OH:11]Participants
5
Reactant 2
Product 1
Reagents, catalysts & solvents 2
Procedure
To a solution of 2-nitrobenzene-1,4-diol (3.00 g, 19.34 mmol) in ethanol (100 mL) was added 10% palladium on carbon (0.600 g, 0.564 mmol). After shaking under 40 psi of hydrogen for 2 hours, the mixture was filtered and the filtrated was concentrated under reduced pressure to provide the product as solid.
Workup
- filtrationthe mixture was filtered
- concentrationthe filtrated was concentrated under reduced pressure
Sources & evidence
- ORD record
- ord-e94f863a59724574881cc682a772c620
- Source dataset
- uspto-grants-2014_02
- Patent number
- US08648087B2
Reaction notes
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