1-Ethylcyclopropanol → Sulfamic acid 1-ethyl-cyclopropyl ester

Reaction equation

[C:1]1([O:7][S:8](=[O:11])(=[O:10])[NH2:9])[CH:6]=[CH:5]C=[CH:3][CH:2]=1.C(C1(O)CC1)C>>[CH2:6]([C:1]1([O:7][S:8](=[O:10])(=[O:11])[NH2:9])[CH2:2][CH2:3]1)[CH3:5]

Participants

Reactant 2

HCID 5450931-Ethylcyclopropanol

HCID 11030308Phenylsulfamate

Product 1

HCID 57785622Sulfamic acid 1-ethyl-cyclopropyl ester

Procedure

Sulfamic acid 1-ethyl-cyclopropyl ester was synthesized according to the method presented in the synthesis of sulfamic acid phenyl ester in Example 1 with the exception of utilizing 1-ethylcyclopropanol (synthesized by methods reported in Synthesis 1991, 234) to obtain sulfamic acid 1-ethyl-cyclopropyl ester.

Workup

customSulfamic acid 1-ethyl-cyclopropyl ester was synthesized

Sources & evidence

ORD record: ord-28e8315f77b64fecafa51d64c0b249b4
Source dataset: uspto-grants-2014_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08809267B2

Reaction notes

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