2-Hex-1-enyl-1H-indole → HCID 14299246, compound
Reaction equation
[CH:1]([C:7]1[NH:8][C:9]2[C:14]([CH:15]=1)=[CH:13][CH:12]=[CH:11][CH:10]=2)=[CH:2][CH2:3][CH2:4][CH2:5][CH3:6].[H][H]>C(O)C.[Pd]>[CH2:1]([C:7]1[NH:8][C:9]2[C:14]([CH:15]=1)=[CH:13][CH:12]=[CH:11][CH:10]=2)[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6]Participants
5
Reactant 2
Product 1
Reagents, catalysts & solvents 2
Procedure
2-Hex-1-enyl-1H-indole was dissolved in ethanol and 10% palladium on carbon was added to the solution. The reaction flask was sealed and exposed to hydrogen gas under pressure and was stirred until the hydrogen gas consumption was completely stopped. The reaction mixture was filtered through Celite. The solvent was evaporated to afford the product.
Workup
- customThe reaction flask was sealed
- filtrationThe reaction mixture was filtered through Celite
- customThe solvent was evaporated
- customto afford the product
Sources & evidence
- ORD record
- ord-804316a7650d49c9a1911361162e534d
- Source dataset
- uspto-grants-2014_08
- Patent number
- US08809382B2
Reaction notes
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