2-Amino-6,7,8,9-tetrahydro-5H-benzo(7)annulen-5-one → HCID 25016804, compound
Reaction equation
[F:1][C:2]1[CH:27]=[CH:26][CH:25]=[C:24]([F:28])[C:3]=1[C:4]([NH:6][C:7]1[CH:8]=[CH:9][C:10]2[C:16]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)=[CH:15][CH2:14][CH2:13][CH2:12][C:11]=2[CH:23]=1)=[O:5].N[C:30]1C=CC2C(=O)C(C)CCCC=2C=1.NC1C=CC2C(=O)CCCCC=2C=1>>[F:1][C:2]1[CH:27]=[CH:26][CH:25]=[C:24]([F:28])[C:3]=1[C:4]([NH:6][C:7]1[CH:8]=[CH:9][C:10]2[C:16]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)=[C:15]([CH3:30])[CH2:14][CH2:13][CH2:12][C:11]=2[CH:23]=1)=[O:5]Participants
4
Procedure
Compound 7 was prepared by a method analogous to the method used to prepare Compound 6 except that 2-amino-6-methyl-6,7,8,9-tetrahydro-benzocyclohepten-5-one (see Allinger, J. Org. Chem. 1962, 27, 70-6) was used as the starting material instead of 2-amino-6,7,8,9-tetrahydro-benzocyclohepten-5-one (g).