Methyl iodide → 3-Methyl-5-isopropylhydantoin

Reaction equation

[CH:1]([CH:4]1[NH:8][C:7](=[O:9])[NH:6][C:5]1=[O:10])([CH3:3])[CH3:2].[CH3:11]I>>[CH:1]([CH:4]1[NH:8][C:7](=[O:9])[N:6]([CH3:11])[C:5]1=[O:10])([CH3:3])[CH3:2]

Participants

Reactant 2

HCID 6328Methyl iodide

HCID 1030335-Isopropylhydantoin

Product 1

HCID 534258423-Methyl-5-isopropylhydantoin

Procedure

Using 5-isopropylimidazolidine-2,4-dione (1.00 g) and methyl iodide (0.46 mL) and by the reaction and treatment in the same manner as in Preparation Example 214, the title compound (0.88 g) was obtained.

Workup

customby the reaction and treatment in the same manner
customas in Preparation Example 214

Sources & evidence

ORD record: ord-12575bc328904eb7885553ff4b5ad664
Source dataset: uspto-grants-2014_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08816079B2

Reaction notes

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