Methyl iodide → 3,5-Dimethyl-2,4-Imidazolidinedione

Reaction equation

[CH3:1][CH:2]1[NH:6][C:5](=[O:7])[NH:4][C:3]1=[O:8].[CH3:9]I>>[CH3:9][N:4]1[C:3](=[O:8])[CH:2]([CH3:1])[NH:6][C:5]1=[O:7]

Participants

Reactant 2

HCID 6328Methyl iodide

HCID 692165-Methylhydantoin

Product 1

HCID 101540613,5-Dimethyl-2,4-Imidazolidinedione

Procedure

Using 5-methylimidazolidine-2,4-dione (1.00 g) and methyl iodide (0.57 mL) and by the reaction and treatment in the same manner as in Preparation Example 214, the title compound (1.66 g, containing DMF) was obtained.

Workup

customby the reaction and treatment in the same manner
customas in Preparation Example 214

Sources & evidence

ORD record: ord-6a391b4510b048bf8b2cb1df12641ef4
Source dataset: uspto-grants-2014_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08816079B2

Reaction notes

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