HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Trifluoromethyl)aniline → 4-methoxy-N-[2-(trifluoromethyl)phenyl]benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Trifluoromethyl)aniline | HCID 6922 | — |
| Reactant | 4-Methoxybenzenesulfonyl chloride | HCID 7401 | — |
| Product | 4-methoxy-N-[2-(trifluoromethyl)phenyl]benzenesulfonamide | HCID 755970 | 75.5% |
Reaction Steps
Using 2-trifluoromethylaniline (1.39 g, 8.55 mmol) and 4-methoxybenzenesulfonyl chloride (1.78 g, 8.55 mmol), the procedure of Reference Example 2 was repeated to obtain 2.14 g (75.5%) of the title compound in the form of colorless solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05728835 |
| Source dataset | uspto-grants-1998_03 |
| ORD ID | ord-a203f03510c84376936109923b3e225b |
| Source note | uspto-grants-1998_03 |