Methanesulfonate → Thieno[2,3-c]pyridin-4-ol

Reaction equation

[CH3:1][S:2]([O-])(=O)=O.[O:6]=[C:7]1[CH2:12][N:11](S(C2C=CC(C)=CC=2)(=O)=O)[CH2:10][C:9]2C=CS[C:8]1=2.[CH2:26](O)C.C1CCCCC1>>[OH:6][C:7]1[CH:12]=[N:11][CH:10]=[C:9]2[S:2][CH:1]=[CH:26][C:8]=12

Participants

Reactant 3

HCID 85257Methanesulfonate

HCID 12751998HCID 12751998, compound

HCID 21585052HCID 21585052, compound

Product 1

HCID 13019694Thieno[2,3-c]pyridin-4-olYield 80%

Procedure

This compound is prepared according to the procedure of Example 1(c), from the methanesulfonate described in (b) above (Yield: 80%). White crystals; M.p.=206° C. (ethanol-cyclohexane)

Workup

customThis compound is prepared

Sources & evidence

ORD record: ord-c7fa9105a70f4e15bd7b2202c93b682b
Source dataset: uspto-grants-1985_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04496568

Reaction notes

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