Tetrafluoro-m-phenylenediamine dihydrochloride → 2,3,4,9-Tetrahydro-2-[4-(4-Pyridinyl)butyl]-1H-Pyrido[3,4-b]Indole Dihydrochloride

HRID 2413720

Reaction equation

HRID 2413720 reaction equation
Br.[N:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1CCCCBr.[C:13]1([NH2:24])[C:18](F)=[C:17](F)[C:16](F)=[C:15](N)[C:14]=1F.[ClH:25].Cl>>[ClH:25].[ClH:25].[N:2]1[CH:7]=[CH:6][C:5]([CH2:3][CH2:4][CH2:5][CH2:6][N:2]2[CH2:3][CH2:4][C:5]3[C:14]4[C:13](=[CH:18][CH:17]=[CH:16][CH:15]=4)[NH:24][C:6]=3[CH2:7]2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 149026Tetrafluoro-m-phenylenediamine dihydrochlorideHCID 703545584-Pyridinylbutyl bromide hydrobromide

Product 1

HCID 201554152,3,4,9-Tetrahydro-2-[4-(4-Pyridinyl)butyl]-1H-Pyrido[3,4-b]Indole Dihydrochloride

Procedure

The title compound was prepared following the procedure of Example 1 and using 4-pyridinylbutyl bromide hydrobromide instead of 4-picolyl chloride hydrochloride, and was converted to the dihydrochloride, mp 259°-261° C.

Sources & evidence

ORD record
ord-fd765fc7725b47e69aa0f2b152173ab9
Source dataset
uspto-grants-1988_01
Patent number
US04719211

Linked notes

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