HCID 20154461, compound → HCID 70410474, compound
Reaction equation
[C:1]([CH2:5][C:6]1[CH:11]=[CH:10][C:9]([S:12][CH:13]2[CH2:18][CH2:17][CH2:16][C:15](=[O:19])[CH2:14]2)=[CH:8][CH:7]=1)([O:3][CH3:4])=[O:2].C(CCC(C1C=CC(SC2CCCC(=O)C2)=CC=1)=O)(OC)=O>>[C:1]([CH2:5][C:6]1[CH:11]=[CH:10][C:9]([S:12][C@@H:13]2[CH2:18][CH2:17][CH2:16][C@H:15]([OH:19])[CH2:14]2)=[CH:8][CH:7]=1)([O:3][CH3:4])=[O:2]Participants
3
Procedure
Following Step B of Example 6 but substituting the title compound of Step A of this Example for 3-(4-(3-carbomethoxy-1-oxopropyl)phenylthio)cyclohexanone, the title compound was obtained as an oil. NMR (ppm) (CDCl3): 7.33 (2H, d, J=9 Hz, H meta to S), 7.17 (2H, d, J=9 Hz, H ortho to S), 4.00 (1H, m, carbinolic proton). 3.60 (3H, s, CH3O), 3.50 (2H, s, CH2), 1.90-1.30 (8H, m, cyclohexane protons).
Sources & evidence
- ORD record
- ord-c179695ca66349a98255e552db58e38d
- Source dataset
- uspto-grants-1988_01