4-(1H-Pyrazol-1-yl)benzaldehyde → (2E)-3-[4-(4H-1,2,4-Triazol-4-yl)phenyl]-2-propenal

Reaction equation

[N:1]1[N:2]=[CH:3][N:4]([C:6]2[CH:13]=[CH:12][C:9]([CH:10]=O)=[CH:8][CH:7]=2)[CH:5]=1.N1(C2C=C[C:22]([CH:23]=[O:24])=CC=2)C=CC=N1>>[N:1]1[N:2]=[CH:3][N:4]([C:6]2[CH:13]=[CH:12][C:9](/[CH:10]=[CH:22]/[CH:23]=[O:24])=[CH:8][CH:7]=2)[CH:5]=1

Participants

Reactant 2

HCID 27764774-(1H-Pyrazol-1-yl)benzaldehyde

HCID 226310064-(4H-1,2,4-Triazol-4-yl)benzaldehyde

Product 1

HCID 22631182(2E)-3-[4-(4H-1,2,4-Triazol-4-yl)phenyl]-2-propenal

Procedure

The title compound was prepared by a procedure analogous to Reference Example 30 by substituting 4-(4H-1,2,4-triazol-4-yl)-benzaldehyde (prepared as described in WO 98/03476) for the 4-(1H-pyrazol-1-yl)-benzaldehyde of Reference Example 30. MS 200 (M+H)+.

Sources & evidence

ORD record: ord-1b7772d171b648a99d652d7e8b7c6968
Source dataset: uspto-grants-2004_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06825170B2

Reaction notes

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