Sodium Hydroxide → HCID 20446512, compound
Reaction equation
O.Br.[CH3:3][C:4]1[CH:13]=[C:12]([NH2:14])[C:11]([N+:15]([O-:17])=[O:16])=[CH:10][C:5]=1[NH:6][CH2:7][CH2:8][NH2:9].[OH-].[Na+]>O>[CH3:3][C:4]1[CH:13]=[C:12]([NH2:14])[C:11]([N+:15]([O-:17])=[O:16])=[CH:10][C:5]=1[NH:6][CH2:7][CH2:8][NH2:9]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
The hydrobromide thus obtained is dissolved in water. After the solution has been rendered alkaline with the aid of a 2N sodium hydroxide solution, the 2-methyl-4-amino-5-nitro-N-(β-aminoethyl)-aniline is filtered off. After washing with water, drying and recrystallisation from ethyl acetate, the product melts at 115° C.
Workup
- filtrationthe 2-methyl-4-amino-5-nitro-N-(β-aminoethyl)-aniline is filtered off
- washAfter washing with water
- customdrying
- customrecrystallisation from ethyl acetate
Sources & evidence
- ORD record
- ord-93087f51c3d64787900243bbb55a0b3c
- Source dataset
- uspto-grants-1984_09
- Patent number
- US04470826
Reaction notes
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